The gastrointestinal tract (GI tract) is a long, continuous tube that starts at the mouth and ends at the anus. In between, there are a number of organs, including the esophagus, stomach, small intestine, large intestine (colon), and rectum. The GI tract is responsible for digesting food and absorbing nutrients from it. Peptides are small molecules. Peptides have a variety of functions in the body, including helping to break down food and promote healing. Some peptides also have antimicrobial properties, which means they can help fight infections. Peptides are being studied as a potential treatment for a variety of GI disorders, including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and gastroesophageal reflux disease (GERD). Peptides may help to reduce inflammation and promote healing in the GI tract. They may also help to improve symptoms such as pain, diarrhea, and constipation. More research is needed to understand how peptides work and whether they are safe and effective for treating GI disorders.