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Tendons are tough, fibrous tissues that connect muscles to bones. They are responsible for transmitting the force of muscle contraction to the skeleton, and as such, they are subject to a great deal of stress and strain. When a tendon is damaged, it can be very difficult to heal. However, recent research has shown that certain peptides may promote healing of damaged tendons.
Tendon healing peptides (THPs) are short chains of amino acids that stimulate the production of collagen, the main structural protein in tendons. Collagen is essential for tendon strength and integrity, and THPs may help to repair damaged tendons by stimulating collagen production. In one study, THPs were injected into the site of a tendon injury in rats, and it was found that they significantly improved healing compared to controls (1).
THPs may also promote angiogenesis, which is the formation of new blood vessels. This is important because blood vessels are necessary for delivering nutrients and oxygen to the tissue, and thus promoting healing. In another study, THPs were found to increase blood vessel density at the site of a tendon injury in rats (2).Overall, THPs appear to be promising agents for promoting healing of damaged tendons. Further research is needed to determine whether they are effective in humans, but if so, they could potentially improve outcomes for patients with tendon injuries.